BioFabrication Facility 'BFF' from Redwire Launching to ISS

Redwire's BioFabrication Facility (BFF), an upgraded 3D Printer developed by Redwire Corporation is one of the three of the company's payloads being launched to the International Space Station on Sunday.

“The ISS provides a critical testing platform to advance these cutting-edge technologies that are enabling critical investigations from commercial users and the scientific research community that will one day extend to future commercial space stations.”

Redwire Executive Vice President of In-Space Manufacturing and Operations John Vellinger.

The BioFabrication Facility (BFF) 3D prints human cells in space to fabricate complex tissue structures and eventually organs that could one day be used to help patients on Earth. Redwire is working with the Uniformed Services University of the Health Sciences Center for Biotechnology (4DBio3), a biomedical research center that explores and adapts promising biotechnologies for warfighter benefit, to explore how space bioprinting could help treat meniscal injuries, one of the most common orthopedic injuries affecting U.S. military service members. The BFF-Meniscus-2 investigation will leverage BFF and Redwire’s ADvanced Space Experiment Processor (ADSEP) facility, both launching onboard NG-18, to bioprint a human knee meniscus in space that will be studied in a lab following the sample’s return to Earth.

BioFabrication Facility is 'Game-Changing Technology'

“BFF is game-changing technology that could have significant implications for the future of human health and patient care on Earth,” said Redwire Executive Vice President of In-Space Manufacturing and Operations John Vellinger. “The ISS provides a critical testing platform to advance these cutting-edge technologies that are enabling critical investigations from commercial users and the scientific research community that will one day extend to future commercial space stations.”

3D bioprinting entire organs in space to benefit patients on Earth is a long-term goal for BFF. In the near-term, the BioFabrication Facility is also a valuable tool for drug efficacy testing. BFF can print and culture organoids, an artificially grown mass of cells or tissue that resembles an organ. Researchers can test new drug compounds on these organoids and derive meaningful data which can greatly benefit drug development research, disease modeling research and tissue engineering approaches.

Redwire is also launching a plant science investigation, The Epigenetic Adaptation to the Spaceflight Environment – Accumulated Genomic Change Induced by Generations in Space (Plant Habitat-03) investigation, that could help identify the genetic elements that increase the adaptability of plants to spaceflight. The Plant Habitat-03 investigation, which will be conducted using NASA’s Advanced Plant Habitat—an automated plant growth facility managed by Redwire, builds upon Redwire’s three previous successful investigations that grew radishes, chili peppers, and cotton tissue culture in space. This investigation could help develop strategies for adapting crops and other economically important plants for growth in marginal and reclaimed habitats on Earth.

Also launching on this mission is the Asymmetric Sawtooth and Cavity-Enhanced Nucleation-Driven Transport investigation, or PFMI-ASCENT. The investigation seeks to demonstrate a passive cooling system for electronic devices in microgravity using a microstructured surface. The investigation will use NASA’s space-based research furnace, the Pore Formation and Mobility Investigation (PFMI) facility, which is managed by Redwire. The long-term goal of this research is to develop a simple, passive, self-regulating microstructured surface technology for heat sinks used in consumer electronics and avionics. The investigation is a collaboration between researchers at Auburn University and University of California-Davis.

(Images provided with Redwire news release and from file)